The Prognostic Significance of IRF8 Transcripts in Adult Patients with Acute Myeloid Leukemia

Interferon regulatory factor 8 (IRF8) is a transcription factor that plays a critical role in normal hematopoiesis, such that disruption of IRF8 activity promotes leukemogenesis. We and others have identified aberrant expression of IRF8 transcripts, including novel splice variants, in acute myeloid...

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Main Authors: Pogosova-Agadjanyan, Era L., Kopecky, Kenneth J., Ostronoff, Fabiana, Appelbaum, Frederick R., Godwin, John, Lee, Hana, List, Alan F., May, Jennifer J., Oehler, Vivian G., Petersdorf, Steve, Pogosov, Galina L., Radich, Jerald P., Willman, Cheryl L., Meshinchi, Soheil, Stirewalt, Derek L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743845/
https://ncbi.nlm.nih.gov/pubmed/23967110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070812
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