Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AML

Patients with high FLT3 internal tandem duplication allelic ratios (FLT3/ITD-ARs) have a poor prognosis. Single-nucleotide polymorphism/comparative genomic hybridization, single-cell PCR and colony-forming assays were used to evaluate genotypic evolution of high FLT3/ITD-ARs in 85 acute myeloid leuk...

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Detaylı Bibliyografya
Asıl Yazarlar: Stirewalt, D L, Pogosova-Agadjanyan, E L, Tsuchiya, K, Joaquin, J, Meshinchi, S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042297/
https://ncbi.nlm.nih.gov/pubmed/24786392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2014.27
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