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The preferentially expressed antigen in melanoma (PRAME) inhibits myeloid differentiation in normal hematopoietic and leukemic progenitor cells

The preferentially expressed antigen in melanoma (PRAME) is expressed in several hematologic malignancies, but either is not expressed or is expressed at only low levels in normal hematopoietic cells, making it a target for cancer therapy. PRAME is a tumor-associated antigen and has been described a...

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Detalhes bibliográficos
Main Authors: Oehler, Vivian G., Guthrie, Katherine A., Cummings, Carrie L., Sabo, Kathleen, Wood, Brent L., Gooley, Ted, Yang, Taimei, Epping, Mirjam T., Shou, Yaping, Pogosova-Agadjanyan, Era, Ladne, Paula, Stirewalt, Derek L., Abkowitz, Janis L., Radich, Jerald P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759652/
https://ncbi.nlm.nih.gov/pubmed/19625708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-170282
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