Topo IIIα and BLM Act within the Fanconi Anemia Pathway in Response to DNA-Crosslinking Agents

The Bloom protein (BLM) and Topoisomerase IIIα are found in association with proteins of the Fanconi anemia (FA) pathway, a disorder manifesting increased cellular sensitivity to DNA crosslinking agents. In order to determine if the association reflects a functional interaction for the maintenance o...

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Autors principals: Hemphill, A.W., Akkari, Y., Newell, A.H., Schultz, R.A., Grompe, M., North, P.S., Hickson, I.D., Jakobs, P.M., Rennie, S., Pauw, D., Hejna, J., Olson, S.B., Moses, R.E.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2009
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759320/
https://ncbi.nlm.nih.gov/pubmed/19738377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000230001
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