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BLM promotes the activation of Fanconi Anemia signaling pathway

Mutations in the human RecQ helicase, BLM, causes Bloom Syndrome, which is a rare autosomal recessive disorder and characterized by genomic instability and an increased risk of cancer. Fanconi Anemia (FA), resulting from mutations in any of the 19 known FA genes and those yet to be known, is also ch...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Panneerselvam, Jayabal, Wang, Hong, Zhang, Jun, Che, Raymond, Yu, Herbert, Fei, Peiwen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078018/
https://ncbi.nlm.nih.gov/pubmed/27083049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8707
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