Bacterial Porin Disrupts Mitochondrial Membrane Potential and Sensitizes Host Cells to Apoptosis

The bacterial PorB porin, an ATP-binding β-barrel protein of pathogenic Neisseria gonorrhoeae, triggers host cell apoptosis by an unknown mechanism. PorB is targeted to and imported by host cell mitochondria, causing the breakdown of the mitochondrial membrane potential (ΔΨ(m)). Here, we show that P...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Kozjak-Pavlovic, Vera, Dian-Lothrop, Elke A., Meinecke, Michael, Kepp, Oliver, Ross, Katharina, Rajalingam, Krishnaraj, Harsman, Anke, Hauf, Eva, Brinkmann, Volker, Günther, Dirk, Herrmann, Ines, Hurwitz, Robert, Rassow, Joachim, Wagner, Richard, Rudel, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759283/
https://ncbi.nlm.nih.gov/pubmed/19851451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000629
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars