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Bim and Bmf Synergize To Induce Apoptosis in Neisseria Gonorrhoeae Infection

Bcl-2 family proteins including the pro-apoptotic BH3-only proteins are central regulators of apoptotic cell death. Here we show by a focused siRNA miniscreen that the synergistic action of the BH3-only proteins Bim and Bmf is required for apoptosis induced by infection with Neisseria gonorrhoeae (N...

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Detalhes bibliográficos
Main Authors: Kepp, Oliver, Gottschalk, Kathleen, Churin, Yuri, Rajalingam, Krishnaraj, Brinkmann, Volker, Machuy, Nikolaus, Kroemer, Guido, Rudel, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654407/
https://ncbi.nlm.nih.gov/pubmed/19300516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000348
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