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Manipulation of Mouse Embryonic Stem Cells for Knockout Mouse Production

The establishment of mouse embryonic stem (ES) cell liness has allowed for the generation of the knockout mouse. ES cells that are genetically altered in culture can then be manipulated to derive a whole mouse containing the desired mutation. To successfully generate a knockout mouse, however, the E...

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Dades bibliogràfiques
Autors principals: Limaye, Advait, Hall, Bradford, Kulkarni, Ashok B
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759096/
https://ncbi.nlm.nih.gov/pubmed/19731225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471143030.cb1913s44
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