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Defined conditions for propagation and manipulation of mouse embryonic stem cells

The power of mouse embryonic stem (ES) cells to colonise the developing embryo has revolutionised mammalian developmental genetics and stem cell research. This power is vulnerable, however, to the cell culture environment, deficiencies in which can lead to cellular heterogeneity, adaptive phenotypes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Mulas, Carla, Kalkan, Tüzer, von Meyenn, Ferdinand, Leitch, Harry G., Nichols, Jennifer, Smith, Austin
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451320/
https://ncbi.nlm.nih.gov/pubmed/30914406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.173146
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