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Defined conditions for propagation and manipulation of mouse embryonic stem cells

The power of mouse embryonic stem (ES) cells to colonise the developing embryo has revolutionised mammalian developmental genetics and stem cell research. This power is vulnerable, however, to the cell culture environment, deficiencies in which can lead to cellular heterogeneity, adaptive phenotypes...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Mulas, Carla, Kalkan, Tüzer, von Meyenn, Ferdinand, Leitch, Harry G., Nichols, Jennifer, Smith, Austin
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451320/
https://ncbi.nlm.nih.gov/pubmed/30914406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.173146
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