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NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State

Naive mouse embryonic stem cells (ESCs) can develop multiple fates, but the cellular and molecular processes that enable lineage competence are poorly characterized. Here, we investigated progression from the ESC ground state in defined culture. We utilized downregulation of Rex1::GFPd2 to track the...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Mulas, Carla, Kalkan, Tüzer, Smith, Austin
Format: Artigo
Language:Inglês
Published: Elsevier 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511111/
https://ncbi.nlm.nih.gov/pubmed/28669603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.05.033
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