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Overview: Generation of Gene Knockout Mice

The technique of gene targeting allows for the introduction of engineered genetic mutations into a mouse at a determined genomic locus. The process of generating mouse models with targeted mutations was developed through both the discovery of homologous recombination and the isolation of murine embr...

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Dettagli Bibliografici
Autori principali: Hall, Bradford, Limaye, Advait, Kulkarni, Ashok B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782548/
https://ncbi.nlm.nih.gov/pubmed/19731224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471143030.cb1912s44
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