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Overview: Generation of Gene Knockout Mice
The technique of gene targeting allows for the introduction of engineered genetic mutations into a mouse at a determined genomic locus. The process of generating mouse models with targeted mutations was developed through both the discovery of homologous recombination and the isolation of murine embr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782548/ https://ncbi.nlm.nih.gov/pubmed/19731224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471143030.cb1912s44 |
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