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Overview: Generation of Gene Knockout Mice
The technique of gene targeting allows for the introduction of engineered genetic mutations into a mouse at a determined genomic locus. The process of generating mouse models with targeted mutations was developed through both the discovery of homologous recombination and the isolation of murine embr...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782548/ https://ncbi.nlm.nih.gov/pubmed/19731224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471143030.cb1912s44 |
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