Recruitment of Fanconi Anemia and Breast Cancer Proteins to DNA Damage Sites is differentially Governed by Replication

Fanconi anemia (FA) is characterized by cellular hypersensivity to DNA crosslinking agents, but how the Fanconi pathway protects cells from DNA crosslinks and whether FA proteins act directly on crosslinks remains unclear. We developed a chromatin-IP-based strategy termed eChIP and detected associat...

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Detalhes bibliográficos
Main Authors: Shen, Xi, Do, Huong, Li, Yongjian, Chung, Woo-Hyun, Tomasz, Maria, de Winter, Johan P., Xia, Bing, Elledge, Stephen J., Wang, Weidong, Li, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758766/
https://ncbi.nlm.nih.gov/pubmed/19748364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.034
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