Dual Inhibition of Mitogen-Activated Protein Kinase Kinase and Mammalian Target of Rapamycin in Differentiated and Anaplastic Thyroid Cancer

Context: Differentiated thyroid cancer and anaplastic thyroid cancer tumors frequently have activation of the ras/raf /MAPK kinase (MEK)/ERK and phosphatidylinositol 3-kinase (PI-3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathways. Objective: The objective of the study was to investigate...

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Autores principales: Jin, Ning, Jiang, Tianyun, Rosen, D. Marc, Nelkin, Barry D., Ball, Douglas W.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Endocrine Society 2009
Materias:
Brief Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758734/
https://ncbi.nlm.nih.gov/pubmed/19723757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-0662
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