Prognostic significance and therapeutic potential of the activation of anaplastic lymphoma kinase/protein kinase B/mammalian target of rapamycin signaling pathway in anaplastic large cell lymphoma

BACKGROUD: Activation of the protein kinase B/mammalian target of rapamycin (AKT/mTOR) pathway has been demonstrated to be involved in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-mediated tumorigenesis in anaplastic large cell lymphoma (ALCL) and correlated with unfavorable outcome in certain...

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Detalhes bibliográficos
Main Authors: Gao, Ju, Yin, Minzhi, Zhu, Yiping, Gu, Ling, Zhang, Yanle, Li, Qiang, Jia, Cangsong, Ma, Zhigui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852000/
https://ncbi.nlm.nih.gov/pubmed/24112608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-471
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