Activation of Mammalian Target of Rapamycin Signaling Pathway Contributes to Tumor Cell Survival in Anaplastic Lymphoma Kinase–Positive Anaplastic Large Cell Lymphoma

Anaplastic lymphoma kinase (ALK)–positive anaplastic large cell lymphoma (ALCL) frequently carries the t(2;5)(p23;q35) resulting in aberrant expression of chimeric nucleophosmin-ALK. Previously, nucleophosmin-ALK has been shown to activate phosphatidylinositol 3-kinase (PI3K) and its downstream effe...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Vega, Francisco, Medeiros, L. Jeffrey, Leventaki, Vasiliki, Atwell, Coralyn, Cho-Vega, Jeong Hee, Tian, Ling, Claret, Francois-Xavier, Rassidakis, George Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839264/
https://ncbi.nlm.nih.gov/pubmed/16818631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-3018
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