Constitutive control of AKT-1 gene expression by JUNB / CJUN in ALK+ anaplastic large cell lymphoma: a novel crosstalk mechanism

Anaplastic lymphoma kinase-positive (ALK+) anaplastic large cell lymphoma (ALCL) is an aggressive T-cell non-Hodgkin lymphoma characterized by the t(2;5) resulting in overexpression of NPM-ALK, which is known to activate the phosphatidylinositol-3-kinase (PI3K)/AKT/mTOR pathway resulting in cell cyc...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Atsaves, Vassilios, Zhang, Ronghua, Ruder, Dennis, Pan, Yunbao, Leventaki, Vasiliki, Rassidakis, George Z., Claret, Francois X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633353/
https://ncbi.nlm.nih.gov/pubmed/25987255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.127
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