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Crystal structures of two archaeal 8-oxoguanine DNA glycosylases of the Ogg2 family provide structural insight into guanine/8-oxoguanine distinction
Among the four DNA bases, guanine is particularly vulnerable to oxidative damage and the most common oxidative product, 7,8 dihydro-8-oxoguanine (8-oxoG), is the most prevalent lesion observed in DNA molecules. Fortunately, 8-oxoG is recognized and excised by the 8-oxoguanine DNA glycosylase (Ogg) o...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758660/ https://ncbi.nlm.nih.gov/pubmed/19446526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.03.007 |
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