Crystal structures of two archaeal 8-oxoguanine DNA glycosylases of the Ogg2 family provide structural insight into guanine/8-oxoguanine distinction

Among the four DNA bases, guanine is particularly vulnerable to oxidative damage and the most common oxidative product, 7,8 dihydro-8-oxoguanine (8-oxoG), is the most prevalent lesion observed in DNA molecules. Fortunately, 8-oxoG is recognized and excised by the 8-oxoguanine DNA glycosylase (Ogg) o...

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Hlavní autoři: Faucher, Frédérick, Duclos, Stéphanie, Bandaru, Viswanath, Wallace, Susan S., Doublié, Sylvie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758660/
https://ncbi.nlm.nih.gov/pubmed/19446526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.03.007
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