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A Novel Adeno-Associated Viral Variant for Efficient and Selective Intravitreal Transduction of Rat Müller Cells

BACKGROUND: The pathologies of numerous retinal degenerative diseases can be attributed to a multitude of genetic factors, and individualized treatment options for afflicted patients are limited and cost-inefficient. In light of the shared neurodegenerative phenotype among these disorders, a safe an...

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Hlavní autoři: Klimczak, Ryan R., Koerber, James T., Dalkara, Deniz, Flannery, John G., Schaffer, David V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758586/
https://ncbi.nlm.nih.gov/pubmed/19826483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007467
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