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Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

Leptin is an adipocyte-derived cytokine that regulates food intake and body weight via interaction with its Ob receptor (ObR). Serum leptin levels are chronically elevated in obese humans, suggesting that obesity may be associated with leptin resistance and the inability to generate an adequate ObR...

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Detalhes bibliográficos
Main Authors: Carpenter, Laura Rocco, Farruggella, Thomas J., Symes, Aviva, Karow, Margaret L., Yancopoulos, George D., Stahl, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27585/
https://ncbi.nlm.nih.gov/pubmed/9600917
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