Role of SH2-Containing Tyrosine Phosphatase Shp2 in Mouse Corneal Epithelial Stratification

PURPOSE. Shp2 protein tyrosine phosphatase mediates a wide variety of receptor tyrosine kinases (RTK) cell signaling. Herein, we investigate the role of Shp2 in corneal morphogenesis and homeostasis. METHODS. Shp2 was conditionally knocked out (Shp2(cko)) in Krt14-rtTA;tet-O-Cre;Shp2(f/f) triple tra...

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Autors principals: Ng, Gracia Y., Yeh, Lung-Kun, Zhang, Yujin, Liu, HongShan, Feng, Gen-Sheng, Kao, Winston W. Y., Liu, Chia-Yang
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850669/
https://ncbi.nlm.nih.gov/pubmed/24204042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12646
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