Llwytho...

C-1027, a radiomimetic enediyne anti-cancer drug, preferentially targets hypoxic cells

The hypoxic nature of cells within solid tumors limits the efficacy of anti-cancer therapies such as ionizing radiation and conventional radiomimetics because their mechanisms require oxygen to induce lethal DNA breaks. For example, the conventional radiomimetic enediyne neocarzinostatin is 4 fold l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beerman, Terry A., Gawron, Loretta S., Shin, Seulkih, Shen, Ben, McHugh, Mary M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758494/
https://ncbi.nlm.nih.gov/pubmed/19147573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2753
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