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Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau

Tau is a microtubule-associated protein that promotes microtubule assembly and stability. In Alzheimer's disease and related tauopathies, tau fibrillizes and aggregates into neurofibrillary tangles. Recently, oleocanthal isolated from extra virgin olive oil was found to display non-steroidal an...

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Detalhes bibliográficos
Main Authors: Li, Wenkai, Sperry, Jeffrey B., Crowe, Alex, Trojanowski, John Q., Smith, Amos B., Lee, Virginia M.-Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758489/
https://ncbi.nlm.nih.gov/pubmed/19549281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06224.x
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