Strategy to Prevent Drug-Related Hypersensitivity in Folate-Targeted Hapten Immunotherapy of Cancer

Cancer vaccine/immunotherapy rarely involves systemic administration of an immunogenic compound to an actively immunized host. We have developed such a strategy that utilizes folate to deliver antigenic haptens [e.g., fluorescein (FITC) and dinitrophenyl] to folate receptor-positive tumors in a hapt...

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Detalhes bibliográficos
Main Authors: Lu, Yingjuan, Klein, Patrick J., Westrick, Elaine, Xu, Le-Cun, Santhapuram, Hari Krishna R., Bloomfield, Alicia, Howard, Stephen J., Vlahov, Iontcho R., Ellis, P. Ron, Low, Philip S., Leamon, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758132/
https://ncbi.nlm.nih.gov/pubmed/19728104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9139-7
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