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Short Communication: R(+)XK469 inhibits hydroxylation of S-warfarin by CYP2C9
INTRODUCTION: XK469 is a novel topoisomerase II inhibitor structurally akin to several propionic acid derivatives, such as ibuprofen and diclofenac, which are metabolized by CYP2C9. We report eight subjects who experienced significant elevation of INR while receiving concomitant R(+)XK469 and warfar...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758059/ https://ncbi.nlm.nih.gov/pubmed/19464879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2009.04.032 |
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