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E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance
T cell unresponsiveness or anergy is one of the mechanisms that maintain inactivity of self-reactive lymphocytes. E3 ubiquitin ligases are important mediators of the anergic state. The RING finger E3 ligase GRAIL is thought to selectively function in anergic T cells but its mechanism of action and i...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757842/ https://ncbi.nlm.nih.gov/pubmed/19805371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908957106 |
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