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The E3 ubiquitin ligase Itch controls the protein stability of p63

p63, a member of the p53 family of transcription factors, plays an important role in epithelial development, regulating both cell cycle and apoptosis. Even though p63 activity is regulated mainly at the posttranslational level, the control of p63 protein stability is far from being fully understood....

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Detalhes bibliográficos
Main Authors: Rossi, Mario, Aqeilan, Rami I., Neale, Michael, Candi, Eleonora, Salomoni, Paolo, Knight, Richard A., Croce, Carlo M., Melino, Gerry
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550770/
https://ncbi.nlm.nih.gov/pubmed/16908849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603449103
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