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The E3 ubiquitin ligase Itch controls the protein stability of p63

p63, a member of the p53 family of transcription factors, plays an important role in epithelial development, regulating both cell cycle and apoptosis. Even though p63 activity is regulated mainly at the posttranslational level, the control of p63 protein stability is far from being fully understood....

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Autors principals: Rossi, Mario, Aqeilan, Rami I., Neale, Michael, Candi, Eleonora, Salomoni, Paolo, Knight, Richard A., Croce, Carlo M., Melino, Gerry
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550770/
https://ncbi.nlm.nih.gov/pubmed/16908849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603449103
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