Llwytho...
p63 threonine phosphorylation signals the interaction with the WW domain of the E3 ligase Itch
Both in epithelial development as well as in epithelial cancers, the p53 family member p63 plays a crucial role acting as a master transcriptional regulator. P63 steady state protein levels are regulated by the E3 ubiquitin ligase Itch, via a physical interaction between the PPxY consensus sequence...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Cell Cycle |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Taylor & Francis
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613134/ https://ncbi.nlm.nih.gov/pubmed/25485500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.951285 |
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