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c-Cbl deficiency leads to diminished lymphocyte development and functions in an age-dependent manner
Aging is broadly defined as a progressive decline of tissue and organ functions due to deregulation of various cell intrinsic and extrinsic factors. In the immune system, aging preferentially affects lymphopoiesis and thus results in the reduced competence of the adaptive immune system in the elderl...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889568/ https://ncbi.nlm.nih.gov/pubmed/20404156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914496107 |
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