Loading...

A scrapie-like unfolding intermediate of the prion protein domain PrP(121–231) induced by acidic pH

The infectious agent of transmissible spongiform encephalopathies is believed to consist of an oligomeric isoform, PrP(Sc), of the monomeric cellular prion protein, PrP(C). The conversion of PrP(C) to PrP(Sc) is characterized by a decrease in α-helical structure, an increase in β-sheet content, and...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hornemann, Simone, Glockshuber, Rudi
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC27576/
https://ncbi.nlm.nih.gov/pubmed/9600908
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!