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[(3)H]Epibatidine Photolabels Non-equivalent Amino Acids in the Agonist Binding Site of Torpedo and α4β2 Nicotinic Acetylcholine Receptors

Nicotinic acetylcholine receptor (nAChR) agonists, such as epibatidine and its molecular derivatives, are potential therapeutic agents for a variety of neurological disorders. In order to identify determinants for subtype-selective agonist binding, it is important to determine whether an agonist bin...

詳細記述

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書誌詳細
主要な著者: Srivastava, Shouryadeep, Hamouda, Ayman K., Pandhare, Akash, Duddempudi, Phaneendra K., Sanghvi, Mitesh, Cohen, Jonathan B., Blanton, Michael P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757197/
https://ncbi.nlm.nih.gov/pubmed/19620239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019083
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