Conditional Ablation of Mediator Subunit MED1 (MED1/PPARBP) Gene in Mouse Liver Attenuates Glucocorticoid Receptor Agonist Dexamethasone-Induced Hepatic Steatosis

Glucocorticoid receptor (GR) agonist dexamethasone (Dex) induces hepatic steatosis and enhances constitutive androstane receptor (CAR) expression in the liver. CAR is known to worsen hepatic injury in nonalcoholic hepatic steatosis. Because transcription coactivator MED1/PPARBP gene is required for...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Jia, Yuzhi, Viswakarma, Navin, Fu, Tao, Yu, Songtao, Rao, M. Sambasiva, Borensztajn, Jayme, Reddy, Janardan K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cognizant Communication Corporation 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756817/
https://ncbi.nlm.nih.gov/pubmed/19630272
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky