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Discovery of Diphenyl Amine Based Sodium Channel Blockers, Effective Against hNa(v)1.2
The development of new therapies for chronic pain is an area of unmet medical need. Central to pathways of chronic pain is the upregulation of voltage gated sodium channels. The use of tricyclic antidepressants, which also have sodium channel activity, in chronic pain therapy prompted us to develop...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756728/ https://ncbi.nlm.nih.gov/pubmed/17035036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.09.010 |
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