Toward Fully Synthetic Homogeneous β-Human Follicle-Stimulating Hormone (β-hFSH) with a Biantennary N-linked Dodecasaccharide. Synthesis of β-hFSH with Chitobiose Units at the Natural Linkage Sites

A highly convergent synthesis of the sialic acid rich biantennary N-linked glycan found in human glycoprotein hormones, and its use in the synthesis of a fragment derived from the β-domain of human Follicle-Stimulating Hormone (hFSH) are described. The synthesis highlights the use of the Sinaÿ radic...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nagorny, Pavel, Fasching, Bernhard, Li, Xuechen, Chen, Gong, Aussedat, Baptiste, Danishefsky, Samuel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756579/
https://ncbi.nlm.nih.gov/pubmed/19341309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja809554x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky