MyosinV controls PTEN function and neuronal cell size

The tumour suppressor PTEN can inhibit proliferation and migration as well as control cell growth in different cell types1. PTEN functions predominately as a lipid phsophatase, converting PI(3,4,5)P(3) to PI(4,5)P(2), thereby antagonizing PI3K (Phosphoinositide 3-kinase) and its established downstre...

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Main Authors: van Diepen, Michiel, Parsons, Maddy, Downes, C. Peter, Leslie, Nicholas R., Hindges, Robert, Eickholt, Britta J
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756284/
https://ncbi.nlm.nih.gov/pubmed/19767745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1961
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