MyosinV controls PTEN function and neuronal cell size

The tumour suppressor PTEN can inhibit proliferation and migration as well as control cell growth in different cell types1. PTEN functions predominately as a lipid phsophatase, converting PI(3,4,5)P(3) to PI(4,5)P(2), thereby antagonizing PI3K (Phosphoinositide 3-kinase) and its established downstre...

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Autori principali: van Diepen, Michiel, Parsons, Maddy, Downes, C. Peter, Leslie, Nicholas R., Hindges, Robert, Eickholt, Britta J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756284/
https://ncbi.nlm.nih.gov/pubmed/19767745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1961
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