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PTEN in Autism and Neurodevelopmental Disorders

Phosphatase and tensin homolog (PTEN) is a classical tumor suppressor that antagonizes phosphatidylinositol 3-phosphate kinase (PI3K)/AKT signaling. Although there is a strong association of PTEN germline mutations with cancer syndromes, they have also been described in a subset of patients with aut...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Rademacher, Sebastian, Eickholt, Britta J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824399/
https://ncbi.nlm.nih.gov/pubmed/31427284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036780
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