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Harnessing PTEN’s Growth Potential in Neuronal Development and Disease

PTEN is a powerful regulator of neuronal growth. It globally suppresses axon extension and branching during both nervous system development and regeneration, by antagonizing growth-promoting PI3K/PI(3,4,5)P(3) signaling. We recently identified that the transmembrane protein PRG2/LPPR3 functions as a...

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Bibliographic Details
Published in:Neurosci Insights
Main Authors: Fuchs, Joachim, Eickholt, Britta J., Leondaritis, George
Format: Artigo
Language:Inglês
Published: SAGE Publications 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493229/
https://ncbi.nlm.nih.gov/pubmed/32974612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2633105520959056
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