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Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders
PTEN is a lipid and protein phosphatase that regulates a diverse range of cellular mechanisms. PTEN is mainly present in the cytosol and transiently associates with the plasma membrane to dephosphorylate PI(3,4,5)P3, thereby antagonizing the PI3-Kinase signaling pathway. Recently, PTEN has been show...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978343/ https://ncbi.nlm.nih.gov/pubmed/24744697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00023 |
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