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Lack of specific γ-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation

Retroviral transduction of tumor antigen-specific T-cell receptor (TCR) genes into lymphocytes redirects T cells to lyse tumors. Furthermore, adoptive transfer of these lymphocytes has mediated objective responses in patients with metastatic cancer. From 2004 to 2006, more than 40 patients were trea...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Burns, William R., Zheng, Zhili, Rosenberg, Steven A., Morgan, Richard A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756199/
https://ncbi.nlm.nih.gov/pubmed/19589923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-199216
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