Evaluation of γ-retroviral vectors that mediate the inducible expression of IL-12 for clinical application

The clinical application of interleukin 12 (IL-12) has been hindered by the toxicity associated with its systemic administration. To potentially overcome this problem, we developed a promoter designed to direct IL-12 expression within the tumor environment using an inducible composite promoter conta...

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Detalhes bibliográficos
Main Authors: Zhang, Ling, Feldman, Steven A, Zheng, Zhili, Chinnasamy, Nachimuthu, Xu, Hui, Nahvi, Azam V, Dudley, Mark E, Rosenberg, Steven A, Morgan, Richard A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358728/
https://ncbi.nlm.nih.gov/pubmed/22576348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31825898e8
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