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Gamma-Retroviral Vector Design for the Co-Expression of Artificial microRNAs and Therapeutic Proteins

To generate γ-retroviral vectors for stable conjoint expression of artificial microRNAs (amiR) and therapeutic genes in primary human lymphocytes, and to identify the design parameters that are key for successful vector generation. Gamma-retroviral vectors were designed to co-express both amiRs and...

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Autori principali: Park, Tristen S., Abate-Daga, Daniel, Zhang, Ling, Zheng, Zhili, Morgan, Richard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162432/
https://ncbi.nlm.nih.gov/pubmed/25019196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2014.0486
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