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Gamma-Retroviral Vector Design for the Co-Expression of Artificial microRNAs and Therapeutic Proteins

To generate γ-retroviral vectors for stable conjoint expression of artificial microRNAs (amiR) and therapeutic genes in primary human lymphocytes, and to identify the design parameters that are key for successful vector generation. Gamma-retroviral vectors were designed to co-express both amiRs and...

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Bibliografiska uppgifter
Huvudupphovsmän: Park, Tristen S., Abate-Daga, Daniel, Zhang, Ling, Zheng, Zhili, Morgan, Richard A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162432/
https://ncbi.nlm.nih.gov/pubmed/25019196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2014.0486
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