Development of Improved Adenosine Deaminase Retroviral Vectors

A series of adenosine deaminase (ADA) retroviral vectors were designed and constructed with the goal of improved performance over the PA317/LASN vector currently used in clinical trials. First, the bacterial selectable-marker neomycin phosphotransferase (neo) gene was removed to create a “simplified...

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Autori principali: Onodera, Masafumi, Nelson, David M., Yachie, Akihiro, Jagadeesh, G. Jayashree, Bunnell, Bruce A., Morgan, Richard A., Blaese, R. Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
Soggetti:
Gene Therapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109465/
https://ncbi.nlm.nih.gov/pubmed/9499026
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