Development of Improved Adenosine Deaminase Retroviral Vectors

A series of adenosine deaminase (ADA) retroviral vectors were designed and constructed with the goal of improved performance over the PA317/LASN vector currently used in clinical trials. First, the bacterial selectable-marker neomycin phosphotransferase (neo) gene was removed to create a “simplified...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Onodera, Masafumi, Nelson, David M., Yachie, Akihiro, Jagadeesh, G. Jayashree, Bunnell, Bruce A., Morgan, Richard A., Blaese, R. Michael
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Gene Therapy
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109465/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9499026/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.3.1769-1774.1998
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