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Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17

The metalloprotease ADAM17 (a.k.a. TACE) plays a pivotal role in the cleavage and activation of membrane-anchored receptor ligands. More recently, it has been revealed that ADAM17 is a potent sheddase of the epidermal growth factor (EGF) family of ligands and regulates epidermal growth factor recept...

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Autors principals: Katakowski, Mark, Jiang, Feng, Zheng, XuGuang, Gutierrez, Jorge A., Szalad, Alexandra, Chopp, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756136/
https://ncbi.nlm.nih.gov/pubmed/19515085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2009.01221.x
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