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Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia
BACKGROUND: Expression of the Sp1 transcription factor is induced by hypoxia, and the ADAM17 promoter contains predicted Sp1 binding sites. ADAM17 contributes to hypoxic-induce invasiveness of glioma. In this study, we investigated whether Sp1 transcription factor induces ADAM17 and/or contributes t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758847/ https://ncbi.nlm.nih.gov/pubmed/19772640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-28-129 |
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