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MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells

MicroRNAs are important regulators of gene expression and have been suggested to play a key role in tumorigenesis. In this study, we show that miR-145 is significantly downregulated in glioma cell lines compared to normal brain tissue and negatively regulates tumorigenesis. Restoration of miR-145 in...

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Detalhes bibliográficos
Main Authors: LU, YONG, CHOPP, MICHAEL, ZHENG, XUGUANG, KATAKOWSKI, MARK, BULLER, BENJAMIN, JIANG, FENG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540808/
https://ncbi.nlm.nih.gov/pubmed/23076445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.2084
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