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Evaluating Dual Activity LPA Receptor Pan-Antagonist/Autotaxin Inhibitors as Anti-Cancer Agents in vivo using Engineered Human Tumors

Using an in situ crosslinkable hydrogel that mimics the extracellular matrix (ECM), cancer cells were encapsulated and injected in vivo following a “tumor engineering” strategy for orthotopic xenografts. Specifically, we created several three-dimensional (3-D) human tumor xenografts and evaluated th...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Xu, Xiaoyu, Yang, Guanghui, Zhang, Honglu, Prestwich, Glenn D.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756011/
https://ncbi.nlm.nih.gov/pubmed/19682598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2009.07.006
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